Sophie Bustany
Étudiante en master et doctorante
Université de Caen - UFR Santé
Diplôme
Thèse de l'Université de Caen. 2014Caractérisation des mécanismes de résistance aux traitements anticancéreux des hémopathies malignes exprimant la cycline D1 : impact du microenvironnement tumoral.
Publications
- Body S, Esteve-Arenys A, Miloudi H, Recasens-Zorzo C, Tchakarska G, Moros A, Bustany S, Vidal-Crespo A, Rodriguez V, Lavigne R, Com E, Casanova I, Mangues R, Weigert O, Sanjuan A, Menéndez P, Marcq B, Piquenot JM, Pérez-Galán P, Jardin F, Roué G, Sola B. 2017. Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells. Sci Rep 2017; 7: 13946. PIMD: 29066743
- Bustany S, Bourgeais J, Tchakarska G, Body S, Hérault O, Gouilleux F, Sola B. Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells. Oncotarget 2016; 7: 45214-45224. PMID: 27286258
- Bustany S, Cahu J, Descamps G, Pellat-Deceunynck C, Sola B. Heat shock factor 1 is a potent therapeutic target for enhancing the efficacy of treatments for multiple myeloma with adverse prognosis. J Hematol Oncol 2015; 8: 40. PMID: 25898974
- Bustany S, Cahu J, Guardiola P, Sola B. Cyclin D1 sensitizes myeloma cells to endoplasmic reticulum stress-mediated apoptosis by activating the unfolded protein response pathway. BMC Cancer 2015; 15: 262.PMID: 25881299
- Bustany S, Cahu J, Moros A, Troussard X, Roué G, Sola B. Expression and subcellular localization of cyclin-dependent kinase inhibitor p27 does not correlate with proliferation pattern of mantle lymphoma cells. Leuk Lymphoma 2014; 55: 2204-2206. PMID: 24354680
- [Moros A, Bustany S], Cahu J, Saborit-Villarroya I, Martínez A, Colomer D, [Sola B, Roué G]. Antitumoral activity of lenalidomide in in vitro and in vivo models of mantle cell lymphoma involves the destabilization of cyclin D1/p27KIP1 complexes. Clin Cancer Res 2014; 20: 393-403. PMID: 24178620
- Sola B, Poirot M, de Medina P, Bustany S, Marsaud V, Silvente-Poirot S, Renoir JM. Antiestrogen-binding site ligands induce autophagy in myeloma cells that proceeds through alteration of cholesterol metabolism. Oncotarget 2013; 4: 911-922. PMID:23978789
- Cahu J, Bustany S, Sola B. Senescence-associated secretory phenotype favors the emergence of cancer stem-like cells. Cell Death Dis 2012; 3: e446. PMID: 23254289
- Bustany S, Tchakarska G, Sola B. Cyclin D1 regulates p27(Kip1) stability in B cells. Cell Signal 2011; 23: 171-179. PMID: 20837141
Dernière modification : 20 novembre 2017
Université de Caen Normandie
équipe MICAH
CHU niveau 3 | 5 avenue de la Côte de Nacre | 14032 Caen Cedex 5 | France
équipe MICAH
CHU niveau 3 | 5 avenue de la Côte de Nacre | 14032 Caen Cedex 5 | France
