Microenvironnement et cancers hématologiques

Better understanding of rare lymphoid B-cell hemopathies

Xavier Troussard and Edouard Cornet

Hairy cell leukemia

1/ Creation of a national Hairy Cell Leukemia (HCL) registry.

2/ Study of HCL using the nanostring technology (in collaboration with Thomas Matthes, Hôpital Universitaire de Genève, Suisse).

3/ Study of HCL using NGS (in collaboration with Fabrice Jardin, Rouen). Description of a “trichopanel”.

4/ Genetic characterization of the group of HCL having the IGHV4-34.

Polyclonal lymphocytosis with binucleated lymphocytes

1/ Feeding of the National Observatory of Polyclonal Lymphocytosis with Binucleated Lymphocytes (PLBL)

2/ Study of PLBL using the nanostring technology (in collaboration with Thomas Matthes, Hôpital Universitaire de Genève, Suisse)

3/ Study of the immune defect associated with PLBL.

Chronic lymphoid leukemia

Confirmation of the mutated or non-mutated status of immunoglobulin heavy chain genes by nanostring of patients included in the CLL FMP 2007 protocol.

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Last update : January 11, 2017

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